- James Gallagher
- BBC Health and Science Editor
3 hours ago
Doctors reported that a man in the United States had contracted the Coronavirus twice, and the second infection was more severe than the first.
The 25-year-old required hospital treatment, after lung problems, and has now recovered.
Cases of reinfection are still rare.
But the study by the Lancet Infectious Diseases study raises questions about how much immunity can be built against the virus.
The young man did not suffer from any health problems or known immune deficiency, which made him particularly vulnerable to infection with Covid-19.
Man Injury Chronology:
March 25: First bout of symptoms, including sore throat, cough, headache, nausea and diarrhea.
April 18: He tested positive for the first time.
April 27: The initial symptoms completely disappeared.
May 9 and 26: He tested negative for the virus twice.
May 28: Symptoms appear again, this time including fever, headache, dizziness, cough, nausea and diarrhea.
June 5: He tested positive for the second time, and he is suffering from hypoxia and short of breath.
Scientists say that the young man was infected with Corona virus twice. A comparison of the virus’s genetic code taken during each episode of symptoms showed that they were different, so that the same infection could not be caused by them.
“Our results indicate that the first infection may not necessarily protect against future infection,” said Dr. Mark Banduri of the University of Nevada.
He stressed that “the possibility of re-infection has an important impact on our understanding of Covid-19 immunity.”
He said even people who have recovered should continue to follow guidelines about social distancing, face masks and handwashing.
The second infection with Covid-19 was supposed to be milder, as the body learned to fight the virus the first time.
It remains unclear why the young man, from Nevada, had a severe illness the second time.
He may have been exposed to a higher dose of the virus.
It is also possible that the primary immune response made the second infection worse. This has been documented with diseases such as dengue fever, where the antibodies resulting from infection with one strain of the virus caused problems when infected with another strain.
Professor Paul Hunter, of the University of East Anglia, said the study was “extremely worrying”.
“Given the fact that so far more than 37 million people have been infected, we would have expected that we would have heard of many other incidents if such very early infections with the disease were common,” he added.
He explained, “It is too early to say with certainty what the implications of these results are for any immune program. But these results reinforce the opinion that we still do not know enough about the immune response to this infection.”
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