And the American “United Press International” website stated, in a report published on Wednesday, that this damage appears to be the result of the virus’s ability to directly infect the kidneys, noting that, according to German, Dutch and American researchers, in some cases this damage may continue beyond infection. Covid-19 itself.
The website quoted the author of the study, Director of the Institute for Experimental Medicine at the RWTH University Hospital in Aachen, Germany, Dr. Raphael Kramann, as saying: “Previous studies were able to conclude that the Corona virus infects kidney cells, which we also found, but what was surprising is that That the virus was also associated with the occurrence of fibrosis or scarring of the patient’s kidneys, which is not a small thing because it can destroy the structure of the kidneys and then fail.”
In the study, researchers tracked 89,000 elderly people who had contracted corona, and found a significant increase in the risk of kidney damage among patients who experienced severe symptoms in the hospital, and even those who had a relatively mild infection.
Kraman adds that the main question he and his colleagues worked to answer wasn’t whether COVID-19 could cause kidney damage, because this was already clear, but instead wanted to know if the damage was an indirect byproduct of inflammation. Caused by the immune response to corona, or whether the coronavirus directly infects the kidneys.
To find out, the team used stem cell technology to design miniature kidneys for testing purposes only, and then they exposed the cultured kidney tissue in the laboratory to the Corona virus, and the result was that the virus had caused direct damage to the kidney cells, regardless of any immune response to inflammation, and it resulted in This damage caused scars that persisted even after patients recovered from COVID-19.
The researchers confirmed that the study, the results of which were published in the journal Cell Stem Cell, focused only on the risks of kidney damage associated with severe infection with corona, noting that it is still not clear whether direct infection of kidney tissue will cause similar serious damage among patients who They have a milder infection.
The researchers said that the damage that occurs in the kidneys due to acute infection with Corona leads to the irreversible deterioration of its functions.
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