We know why Covid-19 is so infectious

We know why Covid-19 is so infectious
We know why Covid-19 is so infectious

The Covid-19 continues to claim victims across the world. Months after the appearance of this deadly virus, researchers go from surprise to surprise regarding this disease. The many studies carried out around the world are telling us a little more about SARS-CoV-2, the Covid-19 virus every day.

We know that this virus has a protein called Spike which allows it to attach to ACE2 receptors in human cells. This protein gives it the ability to force entry into our cells and reproduce there.

Photo by Juraj Varga. Pixabay credits

After months of research, researchers at the Technical University of Munich, Germany, and the University of Helsinki, Finland, have discovered another protein that would shed light on why the Covid-19 virus is so infectious .

Towards a better understanding of Covid-19 thanks to neuropilin 1

This protein called neuropilin 1 is found in cells that line the nasal cavities. It is known to signal pain in humans and is involved in the growth of his blood vessels. However, the researchers found that it also played the role of a receptor that facilitates the infection of our tissues by SARS-CoV-2.

“If you think of ACE2 as the door lock to get into the cell, then neuropilin 1 could be the one that directs the virus to the door. ACE2 is expressed at very low levels in most cells. It is therefore not easy for the virus to find doors to enter it. Other factors such as neuropilin 1 could help the virus find its door ”, explained Giuseppe Balistreri, co-author of the study published in the journal Science.

Read also : FDA approves Remdevesir as treatment for Covid-19

Promising results

To make this discovery, the researchers had to go back as Ravi Ojhan, another co-author of the study, explains.

“The starting point of our study was to find out why SARS-CoV, a coronavirus that led to a much smaller outbreak in 2003, and SARS-CoV-2 spread so differently when they use the same main receiver ACE2. “

Experiments carried out on samples taken from deceased patients of Covid-19 and on mice confirmed that neuropilin 1 facilitated the entry of the virus into the nervous system. The researchers plan to use this discovery to develop effective ways to fight the virus.

“Right now, our laboratories are testing the effects of new molecules that we have specially designed to disrupt the connection between the virus and neuropilin. The preliminary results are very promising and we hope to obtain in vivo validations in the near future. “

Read also : Covid-19 is 5 times more deadly than influenza for hospital patients

Source link by https://www.fredzone.org/on-sait-pourquoi-le-covid-19-est-aussi-infectieux-985

*The article has been translated based on the content of Source link by https://www.fredzone.org/on-sait-pourquoi-le-covid-19-est-aussi-infectieux-985
. If there is any problem regarding the content, copyright, please leave a report below the article. We will try to process as quickly as possible to protect the rights of the author. Thank you very much!

*We just want readers to access information more quickly and easily with other multilingual content, instead of information only available in a certain language.

*We always respect the copyright of the content of the author and always include the original link of the source article.If the author disagrees, just leave the report below the article, the article will be edited or deleted at the request of the author. Thanks very much! Best regards!

These were the details of the news We know why Covid-19 is so infectious for this day. We hope that we have succeeded by giving you the full details and information. To follow all our news, you can subscribe to the alerts system or to one of our different systems to provide you with all that is new.

It is also worth noting that the original news has been published and is available at en24news and the editorial team at AlKhaleej Today has confirmed it and it has been modified, and it may have been completely transferred or quoted from it and you can read and follow this news from its main source.

NEXT Top French university loses funding over pro-Palestinian protests