The Liverpool center-back went into the Everton box to attack a free kick when it rattled from Pickford.
VAR glanced at the challenge when Van Dijk was treated and England international Pickford was very lucky not to have been shown a red card.
Dutch defender Van Dijk continued to play for a few minutes but it wasn’t long before he pointed to the bench and was forced to make way.
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The Liverpool center-back has been replaced by Joe Gomez, who was named on the bench on Saturday. Joel Matip made the starting XI.
The injury will be another blow to Klopp, who is currently without goalkeeper Alisson and midfielder Naby Keita.
Liverpool have also had to do without Sadio Mane and Bayern Munich’s new signing Thiago Alcantara in recent weeks, although the couple was out with corona virus.
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However, Mane showed no sign of losing his pace when he returned to the starting XI at Goodison Park on Saturday.
The striker opened the gate for the Reds in just the third minute.
Liverpool’s lead was short-lived, however, when Everton equalized after 20 minutes through Michael Keane, who shot a header past Adrian.
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