Silisão opened the goals in the 16th minute with a Marquinus header before Roberto Firmino scored twice in the 30th and 49th minutes.
Jose Carrasco scored by mistake in the 66th minute, and Felipe Coutinho completed the fifth with a header in the 79th minute.
video:1
In Colombia, Los Cafeteros did not find it difficult to beat their Venezuelan visitors to win 3 goals without response.
Duvan Zapata scored in the 16th minute and Luis Muriel, his teammate at Italian club Atalanta, scored in the 26th and 45th minutes.
video:2
Brazil jumped to the top of the qualifiers on goal difference from runner-up Colombia, third Uruguay and fourth, Argentina.
Brazil hosts Peru on Wednesday and Colombia plays host Chile.
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