Experimenting with antiviral drugs on animals prevents the spread of the...

A new study found that an experimental antiviral drug taken orally, completely suppressed the transmission of the Corona virus within 24 hours from infected animals. According to a report by the British newspaper “Daily Mail”, the so-called drugs molnupiravir They prevent the virus from reproducing, thus preventing it from spreading throughout the body.


A drug for Corona prevents the virus in animals after 24 hours of eating it

The researchers found that the drug prevented rodents infected with Corona from spreading the disease to each other, but those who were not given the drug spread the disease among them.

The team, from Georgia State University, USA, said that if the data could be translated into humans, but this means that Corona patients who receive treatment may become non-infectious within a day.

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“This is the first demonstration of a drug available orally to prevent the rapid transmission of corona,” said Dr. Richard Plimber, a professor at the Institute of Biomedical Sciences in Georgia.

Molnopiravir Molnupiravir It is an antiviral drug developed at a university Emory , In Atlanta, and was originally supposed to treat influenza and prevent the virus from copying itself by creating errors during viral RNA replication.

A study conducted in April 2020 found that the drug “Molnopiravir” can prevent and reduce severe lung damage in mice infected with the Coronavirus.

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The drug is currently undergoing a second / third phase of clinical trials, where it is tested in three different doses every 12 hours for 5 days in patients. COVID-19 However, data is not expected to be available until at least May 2021.

For the new study published in the journal Nature Microbiology In, the team tested the ability of Molnopiravir to stop the virus from spreading to rodents.

Co-author Dr Robert Cox said: “We think that ferrets are a closely related transmission model because they readily spread corona, but they often do not develop severe disease.

Study details

The researchers infected 6 rodents with the Corona virus, and treated 3 of them with the drug when they began to release the virus from their noses, after that, the team took 12 uninfected rodents and two in a cage with one of the sick animals.

The rodents were tested every day for 8 days, and they found that none of the rodents that were in cages had been infected with the animals treated with the virus, however, by the fourth day, all the rodents that were confined fell sick with those who were not treated with the drug.

As infections and deaths continue to rise across the United States, stopping the spread of the virus in society will be a key factor in limiting the epidemic until vaccines are widely available.

The researchers said, “We noticed early on that [مولنوبيرافير] It has broad activity against respiratory RNA viruses, and oral treatment of infected animals with the drug reduces the amount of viral particles falling by several times in volume, which greatly reduces transmission, “Blimber said.

“These characteristics have made it [مولنوبيرافير] A powerful filter for drug control in COVID-19.”

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