According to HSE figures, 349 patients are currently being treated for coronavirus, 38 of whom are in intensive care.
The news comes amid fears that the Irish health system could come under increasing pressure if the number of patients continues to rise.
There are currently only nine ICU beds available in Northern Ireland, according to reports.
Hospital admissions in the republic have risen to levels last seen at the peak of the pandemic this spring, and while death rates have slowed significantly, the surge in hospital admissions is cause for concern.
On Monday, 939 new cases of coronavirus were confirmed nationwide, while three more deaths were reported.
Of the new cases, 444 are men and 483 are women.
66% of the new cases are under 45 years of age.
There are currently 30 Covid-19 patients in Cork University Hospital, 27 in Cavan and 26 in Tallaght University Hospital.
Ireland is now five days after its second full lockdown, with level 5 restrictions going into effect on Thursday last week.
The tough measures are currently in place across the country for six weeks to ease the lockdown by the end of November.
The situation will be reviewed in three weeks, at which point the restrictions could be extended, relaxed or lifted entirely.
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