“We have discovered that the survival of patients who were treated with cyclosporine was higher compared to patients who were not treated with this treatment,” says the head of the Internal Medicine Service of the Quirónsalud Madrid University Hospital and professor at the European University, the Dr. Daniel Carnevali, in statements collected for 20 minutes. During the first months of the first wave of the coronavirus in Spain, many hospitals and health centers experimented with medicines and drugs that were used in other types of diseases with similar symptoms. “Hydroxychloroquine, antivirals like Lopinavir-ritonavir; antibiotics; corticosteroids and drugs that act in the inflammatory phase of the disease such as tozilizumab and cyclosporine, Carnevali cites.
How and when does cyclosporine work?
Cyclosporine is effective in the second phase of the disease, that is, with severe cases when pneumonia develops in the body and the patient is not able to respond adequately to the infection, leaving the lung quite weakened. As cyclosporine is effective in organ donation operations to contain the reaction of the immune system, it is also effective when it is the coronavirus that tries to act against the body.
More than 600 patients have received doses of this drug with positive results according to the study published in the scientific journal The Lancet, although Carnevali warns that it is retrospective: “It is not a randomized, double-blind study that compared drug to drug.” “Patients who have received cyclosporine are not essentially different from the rest,” he adds.
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