The study, which was published in the “Cell” magazine and conducted on 200 people infected with the Corona virus, identified 4 factors for long-term symptoms, the first of which: the level of the RNA of the Corona virus in the blood upon infection, or what is known as “viral load”, according to the newspaper. The New York Times.
The second factor is the presence of some autoantibodies that the body produces to attack the virus, but they mistakenly attack the body’s cells as they do in cases such as lupus and rheumatoid arthritis. The third factor is the reactivation of the Epstein-Barr virus, a virus that infects most people when they are young but over time falls into a state of hibernation.
The study reported that the fourth factor was type 2 diabetes, although researchers and other experts said that in studies with larger numbers of patients, diabetes is not a common cause of long-term symptoms.
“It’s the first real, robust attempt to devise some biological mechanisms to understand the long-term symptoms of corona,” said Dr. Stephen Dicks, a professor of medicine at the University of California, Los Angeles, who was not involved in the study.
But he and other experts cautioned that the findings were exploratory and would need to be verified with more research.
Dr. Dix added: “All four factors are biologically plausible, agree with other theories, and most importantly, each is verifiable.” He indicated that they can be helped as doctors in treating Corona patients better.
“I think this research stresses the importance of taking measurements early in the disease course to know how to treat patients,” said Jim Heath, the study’s lead author.
He added, “We did this analysis because we know patients are going to the doctors and saying they’re tired all the time, and the doctor just tells them to get more sleep. It’s not very helpful. So, we actually wanted to have a way to quantify and say something was wrong. Actually with these patients.”
The complex study involved several components and involved dozens of researchers at several universities and centers, including the Institute for Systems Biology, the University of Washington and the Swedish Medical Center in Seattle.
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