Influence of pre-existing diseases on COVID-19 infection and the role of...

The whole world is suffering from a new type of viral disease caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The present article briefly discussed genome sequencing and host cell interaction with SARS-CoV-2. The influence of pre-existing diseases such as diabetes, heart disease and patient age on COVID-19 infection is being investigated. The possible treatments for SARS-CoV-2, including antiviral drugs, traditional Chinese treatment, and plasma therapy, are discussed at length. The right vaccine against COVID-19 is still not available. The experiments with existing antiviral vaccines such as chloroquine / hydroxychloroquine, remdesivir, ritonavir and lopinavir and their consequences are briefly presented. It also explored the importance of new materials and devices in the detection and treatment of COVID-19. The polymerase chain reaction (PCR) based and non-PCR based devices are used to detect COVID-19 infection. The non-PCR based instruments provide quick results compared to the PCR based instruments.

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