October 18, 2020 1:30:48 p.m.
The estimated incidence of breast cancer in India increased 6% from 1.42 lakh in 2016 to 1.51 lakh in 2017. (Photo: Getty / Thinkstock)
Did you know that chest Cancer is the second most common health problem in India after cardiovascular disease? India has also seen an increase, with over 1.46 million cases worldwide Breast cancer Cases that affect at least one in 22 women in the country. While the disease predominantly affects women, regular cases of male breast cancer have also been reported Dr. Niti Raizada, Director, Medical Oncology and Hemato-Oncology, Fortis Cancer Institute, Bangalore.
Dr. Raizada says that at least “five It is known that 10 percent of breast cancer cases are hereditary, which is due to abnormal genes passed from parent to child. Individuals with hereditary breast cancer (HBOC) inherit the germline mutation in the BRCA1 or BRCA2 gene, or some form of rare genetic mutations such as PALB2TP53, ATM, PTEN, CDH1, etc. ”However, the risk of a particular cancer increases over a lifetime.
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BRCA1 and BRCA2 gene cancer risks
Dr. Raizada explains how a greater number of congenital breast cancer cases are linked to mutations in two genes: BRCA1 (Breast cancer gene one) and BRCA2 (Breast cancer gene two).
Both cancer genes are known Repair cell damage and encourage breast, ovarian and other cells to grow. “However, if these genes contain mutations that are passed down through generations, the genes are unlikely to function normally, which increases the risk of breast, ovarian and other cancers. That is, women who are diagnosed with breast cancer and who have either BRCA Mutations likely have a family history of breast cancer, ”says Dr. Raizada.
She explains that if you’ve inherited a mutated copy of one of the genes from one of your parents, the chances of getting breast cancer, whether it’s ovarian cancer, pancreatic cancer, or even prostate cancer in men, increase. “If you have a BRCA1 or BRCA2 gene mutation, the likelihood of an increase in breast cancer by the age of 80 is likely. In addition, the risk also depends on the number of family members who have had breast cancer, ”says the doctor. Unfortunately, it is precisely this gene mutation that increases the likelihood of bBreast cancer was diagnosed at a younger age.
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However, it is equally important to understand that the majority of women diagnosed with breast cancer do not have a family history of the disease. It is the women who have close blood relatives with breast cancer who are at higher risk, like. When a woman has one First-degree relatives with breast cancer or someone who has a father or brother with breast cancer are at higher risk of developing breast cancer.
“If you’ve had cancer in one breast, the risk of developing new cancer in the other breast or part of the same breast is high,” adds the doctor.
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Make sure to use these tips to self-examine your breasts. Check it out here.
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