Abstract
background
Being overweight shortens life expectancy. Bariatric surgery is known to reduce the long-term relative risk of death, but its impact on life expectancy is unclear.
Methods
We used the Gompertz proportional risk regression model to compare mortality and life expectancy in patients who had either had bariatric surgery (surgery group) or standard obesity treatment (control group) in the prospective controlled Swedish study of obese subjects (SOS) and Participants in the SOS were treated to a reference study (reference cohort), a random sample from the general population.
Results
A total of 2007 and 2040 patients were included in the operation group and control group, respectively, and 1135 participants were included in the reference cohort. At the time of the analysis (December 31, 2018), the median follow-up duration for mortality was 24 years (interquartile range 22 to 27) in the surgery group and 22 years (interquartile range 21 to 27) in the control group; Mortality data were available for 99.9% of the patients in the study. In the SOS reference cohort, the median follow-up duration was 20 years (interquartile range 19 to 21) and mortality data were available for 100% of participants. A total of 457 patients (22.8%) died in the operation group and 539 patients (26.4%) in the control group (hazard ratio, 0.77; 95% confidence interval) [CI]0.68 bus 0.87; P
Conclusions
In obese patients, bariatric surgery was associated with a longer life expectancy than standard obesity care. Mortality remained higher in both groups than in the general population. (Funded by the Swedish Research Council and others; SOS ClinicalTrials.gov number, NCT01479452.)
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Life Expectancy After Bariatric Surgery
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