Coronavirus: Dubai medical authority shuns finger prick blood tests over accuracy concerns

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Hind Al Soulia - Riyadh - A quick test to check if someone has immunity to the coronavirus will not be used in Dubai until more reliable kits are found.

Dubai Health Authority said the trusted polymerase chain reaction (PCR) test - using a nasal swab sample - will be the sole method of testing.

Officials said they were aware of significant variations in quality and that expert opinion over the tests remained divided.

A testing push in Spain in March turned into a scandal when the initial batch had a 30 per cent accuracy rate, instead of 80 per cent as the manufacturer claimed. In the United States, there has been criticism of the quality of tests coming from China after the Food and Drug Administration (FDA) relaxed rules governing medical equipment.

There are many different antibody tests that have been developed and marketed, with considerable variability in their accuracy

Dr Andrew Freedman, School of Medicine, Cardiff University

DHA said it was "closely following global developments on Covid-19, including testing protocols for the disease... in order to provide the best diagnosis and healthcare for citizens and residents".

It said any use of "rapid antibody testing has not been universally adopted" and would not be used any longer.

Emirates said it was the first airline globally to use rapid testing kits to check passengers before boarding flights, first to Tunisia last month and in recent Indian repatriation flights. Testing stations were set up with the DHA inside terminals to allow results in 10 minutes.

Rapid blood tests do not determine whether someone has the virus at the time, but whether they had it in the past and built up immunity.

Nationwide, healthcare providers have since been banned from using or selling rapid screening kits due to their inaccuracy.

“The devices used in these tests have not been proven effective for demonstrating infection with the Covid-19 virus,” a statement from the Department of Health said.

Medics test a child at the Dubai International Airport before boarding a flight to Kerala. AFP

Indian citizens leaving the Kochi International Airport. The first repatriation flight came from Abu Dhabi on May 7. AFP

A sick passenger being taken to a hospital after arriving from Abu Dhabi at the Kochi International Airport. AFP

Passengers queue for check-in on Thursday for the first of ten flights between the UAE and India in the next week. AFP

A mother carries a sleeping child through terminal 2. AFP

Stranded tourists and pregnant women were among those given priority for the first of 10 planned flights. AFP

Health workers conduct temperature and blood tests as passengers arrive at the terminal. AFP

Passengers wait for flights at Dubai International Airport on Thursday afternoon. Indian Consulate

Passengers wait for flights at Dubai International Airport on Thursday afternoon. Indian Consulate

Relatives and friends of Indian passengers outside the Terminal 2 departure gate as India stages it largest repatriation mission. Pawan Singh / The National

First flights took off from Abu Dhabi and Dubai on Thursday. Pawan Singh / The National

Relatives and friends of Indian passengers. Pawan Singh / The National

Medical staff were present to test all individuals before they boarded their flights. Indian Consulate

Passengers were tested before boarding the flights. Indian Consulate

Passengers wait for the flights at Dubai International Airport on Thursday. Indian Consulate

The first repatriation flight went to southern India's Kerala state. Indian Consulate

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The World Health Organisation recommends limiting the use of rapid testing to epidemiological monitoring in surveys, research and studies.

“There are many different antibody tests that have been developed and marketed, with considerable variability in their accuracy,” said Dr Andrew Freedman, an expert in infectious diseases at Cardiff University's College of Biomedical and Life Sciences.

“Of particular concern are those with low specificity resulting in an unacceptably high false positivity rate; this would mean some people may be wrongly told they have had the infection and therefore probably immune.

“In general, the ones that involve sending a blood sample to be tested in a lab perform much better then the rapid, point-of-care test kits.”

Nasal swabs are the most effective test for Covid-19, although progress is being made on reliable antibody blood tests that could prove if someone is immune from the virus. AFP
Nasal swabs are the most effective test for Covid-19, although results often take days. AFP

Aside from concerns that antibody tests appear to have been misunderstood or misused, the ability to determine how much immunity a person has is also debatable.

An article in the respected medical journal The Lancet said immunity passports could become the norm for travellers in future.

Digital or physical documents confirming if an individual had the virus and recovered have been suggested in Chile, Germany, Italy, the UK and America.

But the WHO warned against both an over-reliance on testing to end lockdowns, and against any document that could prove someone was protected.

Newer 'more accurate' testing

In the UK, Public Health England has approved a blood test for antibodies it claims is 100 per cent effective.

The testing kits by Swiss manufacturer Roche were claimed to be a “game changer” in lifting travel and work restrictions in the country.

The approval has opened the gates for a mass National Health Service antibody testing programme to find out who has already had the virus and is at less risk of passing it on to others.

Coronavirus outbreak

Although there are still many unknowns about Covid-19, there is strong evidence to suggest those who have had the virus could be immune for two to three years.

The kits have also received emergency approval in the US.

John Newton, the UK’s national co-ordinator of the programme, said the Roche Sars-CoV-2 serology assay recorded a specificity of 100 per cent in tests.

That is in contrast to many tests that deliver "false positives" are eliminated.

“This is a very positive development because such a highly specific antibody test is a very reliable marker of past infection,” he said.

Reports in the UK suggest it will be the first nation to benefit from a mass inoculation programme, if an effective vaccine is discovered.

British-Swedish drug manufacturer AstraZeneca Plc has committed to producing 30 million doses of coronavirus vaccine to the UK by September, with 100 million by the end of the year.

Developed at the University of Oxford, a potential vaccine is already being studied in humans and could enter late-stage trials by mid-summer, according to reports.

Updated: May 18, 2020 01:55 PM

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