So-called mRNA vaccines are new and raise concerns –
8 hours ago
NÜRNBERG – You are the hope in the fight against the global pandemic: vaccines. But: They also bring a lot of unknowns with them. We reveal what you should know about the topic:
The currently promising vaccine candidates are based on a principle that a virus assembly instructions are smuggled into cells.
What is mRNA
The “m” stands for “messenger”, which means something like “messenger”. RNA is the English abbreviation for “ribonucleic acid”, ie ribonucleic acid. While the genetic material of the cells is stored on the DNA, the deoxyribonucleic acid, the RNA helps to “read” the information. The mRNA carries the genetic message about how a protein should be structured in a cell.
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How does an mRNA vaccine work?
Researchers make use of this principle in vaccine development. They smuggle the building instructions for a protein from the Sars-Cov-2 virus envelope into the cells. The immune system reacts to the template and builds up protection. When the virus actually gets into the body, the immune system is prepared.
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What are DNA Vaccines?
DNA vaccines work on a similar principle to RNA vaccines, but the information is transported into the nucleus and not just into the cell. This could lead to parts of the foreign DNA being built into the body’s own. The process has been researched since the 1990s. So far, DNA-based vaccines have only been approved in veterinary medicine.
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Are mRNA vaccines dangerous?
“Warnings about genetic damage are wrong and cause unfounded fears,” says Klaus Cichutek, President of the Paul Ehrlich Institute. The PEI is responsible for the approval of vaccines in Germany. Fears that the new vaccines could change the genetic material “do not correspond to the state of scientific knowledge”.
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Cichutek also contradicts statements that there are no human medical experience. “There is experience in humans in clinical trials, for example with a therapeutic tumor vaccine,” he explains. “There were no worrying side effects.” Even extensive animal experiments with mRNA vaccines did not reveal any serious side effects or damage. “In order to be incorporated into the DNA, RNA would have to be” translated back “.” This would require two enzymes that normal human cells do not have. “
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