The researchers analyzed data entered into the Strainprint app by people who identified themselves as OCD. This condition is characterized by intrusive, persistent thoughts and repetitive behaviors, such as: B. the compulsory check whether a door is locked. After smoking cannabis, users with obsessive-compulsive disorder reported reducing compulsions by 60%, intruders or unwanted thoughts by 49%, and anxiety by 52%.
The study recently published in the Journal of Affective Disorders also found that higher doses and cannabis with higher concentrations of CBD or cannabidiol were associated with greater reductions in compulsions.
“Overall, the results suggest that cannabis may have some beneficial short-term, but not really long-term effects on obsessive-compulsive disorder,” said Carrie Cuttler, co-author of the study and associate professor of psychology at WSU. “To me, the CBD results are really promising because they are not underwhelming. This is an area of research that would really benefit from clinical trials examining changes in compulsions, interventions, and anxiety with pure CBD. ”
The WSU study relied on data from more than 1,800 cannabis sessions that 87 people had registered with the Strainprint app over a period of 31 months. The long period allowed researchers to assess whether users developed tolerance to cannabis, but these effects were mixed. As people continued to use cannabis, the associated reductions in intrusions became slightly less, suggesting they were building tolerance, but the relationship between cannabis and reductions in compulsions and anxiety remained fairly constant.
Traditional treatments for obsessive-compulsive disorder include exposure and reaction prevention therapy, which directly challenges people’s irrational thoughts about their behavior, and prescribing antidepressants called serotonin reuptake inhibitors to relieve symptoms. While these treatments have beneficial effects for many patients, they do not cure the disorder, nor do they work well for everyone with OCD.
“We are trying to build knowledge about the relationship between cannabis use and OCD because there is really little research into this area,” said Dakota Mauzay, a PhD student in Cuttler’s lab and first author of the paper.
Aside from their own research, the researchers only found one more human study on the subject: a small clinical study of 12 people that found that OCD symptoms were reduced after cannabis use, but were not much greater than those with that Placebo.
The WSU researchers noted that one of the limitations of their study was the inability to use a placebo control and that an “expectation effect” may play a role in results, i.e. when people expect them to be different from something that they generally do feel better. The data also came from a self-selected sample of cannabis users, and the results were mixed, meaning that not everyone experienced the same reduction in symptoms after using cannabis.
However, Cuttler said this analysis of user-provided information through the Strainprint app was especially valuable as it provides a large data set and participants used market cannabis in their home environment as opposed to state-grown cannabis in a laboratory that could affect your answers. Strainprint’s app is designed to help users find out which types of cannabis are best for them. However, the company granted the WSU researchers free access to the anonymized user data for research purposes.
Cuttler said that this study suggests that further research, particularly clinical trials of the CBD component of cannabis, may reveal therapeutic potential for people with obsessive-compulsive disorder.
This is the fourth study in which Cuttler and her colleagues examined the effects of cannabis on various mental illnesses using data from the app created by the Canadian company Strainprint. Others include studies of how cannabis affects PTSD symptoms, relieves headaches, and affects emotional well-being.
(This story was posted by a wire agency feed with no changes to the text.)
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